PeakFit Automatically Places Peaks in Three Ways.

PeakFit uses three procedures to automatically place hidden peaks; while each is a strong solution, one method may work better with some data sets than others.

The Residuals procedure initially places peaks by finding local maxima in a smoothed data stream. Hidden peaks are then optionally added where peaks in the residuals occur.

The Second Derivative procedure searches for local minima within a smoothed second derivative data stream. These local minima often reveal hidden peaks.

The Deconvolution procedure uses a Gaussian response function with a Fourier deconvolution / filtering algorithm. A successfully deconvolved spectrum will consist of “sharpened” peaks of equivalent area. The goal is to enhance the hidden peaks so that each represents a local maximum.